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Magnetic Resonance Imaging as a Surrogate Outcome Measure of Disability in Multiple Sclerosis: Have We Been Overly Harsh in Our Assessment?
Ann Neurol 59:597-605, Goodin,D.S., 2006
See this aricle in Pubmed

Article Abstract
These observations, together with the significant relations already reported between MRI and disability (with observed correlations in the range of 0.2-0.6), actually suggest that our available clinical and MRI measures are considerably better than is currently believed and, in fact, that the MRI may be a valid surrogate marker in the assessment of treatment efficacy in MS.
 
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multiple sclerosis
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treatment of neurologic disorder

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